A database for chicken full-length cDNAs

Studies on full-length cDNAs as one area of Post Genome-Sequence Researches are being carried out for several eukaryotes. Over 20,000 human full-length cDNAs have been recognized. The rapid progress in this field facilitates the following researches in functional genomics and proteomics. The first draft sequence of the chicken genome was released in 2004, shedding light on most of the post-genome researches. The chicken full-length cDNA database is hereby constructed as a platform that bridges bioinformatical groups and experimental groups with the aim of pushing functional genomics research in chicken. The current more than 588,000 chicken ESTs in public databases were utilized to predict chicken full-length cDNA, using the human or mouse full-length cDNAs or ORFs as templates. The human and mouse templates were from NEDO, RIKEN, and MGC. All of the EST alignment outputs on the human and mouse templates were listed in this database. The supplementary information for the predictions given by the EMBL was also provided. The BLAST alignment outputs are useful for experimentally obtaining the full-length cDNAs for chicken genes

The database was implemented into the Bioinfo system under the joint effects from ZhengGang Wang, Yong Wang, Frederick Leung in Department of Zoology and Frankie Cheung, Christine Ho and Nam Ng in Computer Centre of the University of Hong Kong.


 


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Reference: Wang, Y., Z. G. Wang, J. Li, Y. J. Wang and F. C. C. Leung. 2007.

Database for chicken full-length cDNAs. Physiol. Genomics 28: 141-145. [Abstract]

 

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